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Product Name | Interleukin 33 (IL33) (AA 112-270) protein (His tag) |
Description | Interleukin 33 (IL-33) is a 32 kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12 kDa and C-terminal fragment of 18 kDa by cleavage of caspase-1 Synonyms: Interleukin 33, DVS27, NF-HEV, NKHEV, C9orf26, Interleukin-1 family member 11, IL- 1F11, Nuclear factor from high endothelial venules, NFEHEV, DKFZp586H0523, RP11-575C20.2, IL-33, IL33 |
Size | 10 µg |
Concentration | n/a |
Applications | n/a |
Other Names | IL33|C9orf26|DVS27|IL1F11|NF-HEV|NFEHEV|RP11-575C20.2|9230117N10Rik|Il-33|Il1f11|RGD1311155 |
Gene, Accession, CAS # | Gene ID: 90865 |
Catalog # | ABIN805063 |
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Order / More Info | Interleukin 33 (IL33) (AA 112-270) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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