| 产品详情 |
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| Product Name | SAR-125844 |
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| Description | Purity ≥98% by HPLC. MW: 550.63. SAR-125844 is a potent, selective, reversible and ATP-competitive c-MET inhibitor, with an IC50 of 4.2 nM. Displays inhibition of MET autophosphorylation in cell-based assays. Upon intravenous administration, SAR-125844 binds to c-Met, thereby disrupting c-Met-mediated signal transduction pathways.This may result in cell growth inhibition in tumors that overexpress c-Met. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SAR125844; 1-(6-((6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)thio)benzo[d]thiazol-2-yl)-3-(2-morpholinoethyl)urea |
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| Gene, Accession, CAS # | CAS: 1116743-46-4 |
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| Catalog # | B2510 |
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| Order / More Info | SAR-125844 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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