| 产品详情 |
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| Antigenic Specificity | UBD |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to UBD. Ubiquitin D, also called UBD or FAT10 is a protein that in humans is encoded by the UBD gene. This gene is mapped to 6p22.1. Ubiquitin-like protein modifier can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. This gene mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It probably functions as a survival factor. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human UBD, different from the related mouse and rat sequences by five amino acids . |
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| Other Names | FAT10, Diubiquitin, Ubiquitin-like protein FAT10 |
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| Gene, Accession # | UniProt: O15205 |
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| Catalog # | orb138021 |
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| Price | |
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| Order / More Info | UBD Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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