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Product Name | Recombinant Human Neuronal migration protein doublecortin (DCX) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 65.3kDa. Full Length: 1-441aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Doublin; Lissencephalin-X; Lis-X |
Gene, Accession, CAS # | DCX, UniProt: O43602 |
Catalog # | RPC21197 |
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Order / More Info | Recombinant Human Neuronal migration protein doublecortin (DCX) from BIOMATIK |
Product Specific References | n/a |
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