| Edit |   |
| Antigenic Specificity | AIRE |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human, porcine |
| Isotype | n/a |
| Format | purified |
| Size | 100 ug |
| Concentration | n/a |
| Applications | Immunohistochemistry: 2.5 µg/mL, peptide-ELISA: 1:32000, Western Blot: 0.5-1.0 µg/mL |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | AIRE Polyclonal Antibody. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay . Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy . |
| Immunogen | n/a |
| Other Names | AIRE; autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) ; AIRE1; APECED; APS1; APSI; PGA1 ; autoimmune regulator (APECED protein); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE |
| Gene, Accession # | Entrez: 100621659, 326; Uniprot: O43918 |
| Catalog # | PA5-18525 |
| Price | |
| Order / More Info | AIRE Antibody from INVITROGEN ANTIBODIES |
| Product Specific References | n/a |