| 产品详情 |
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| Product Name | Chk2 Inhibitor |
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| Description | MW: 363.8. Purity ≥98% by HPLC. Background: A cell-permeable, potent, and ATP-competitive inhibitor of Chk2 (checkpoint kinase 2; IC?? = 15 nM; Ki = 37 nM). Displays ~1,000-fold greater selectivity for Chk2 compared to Cdk1/cyclin B and CK1 (IC?? = 12 uM and 17 uM, respectively) and only weakly affects the activities of a panel of 31 kinases (< 25% inhibition at 10 uM), including Chk1. Shown to rescue both peripheral CD4+ and CD8+ T-cells from gamma-irradiation-induced apoptosis with an EC?? |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [2-(4-(4-Chlorophenoxy)phenyl)-1H-benzimidazole-5-carboxamide] |
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| Gene, Accession, CAS # | CAS: 516480-79-8 |
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| Catalog # | MBS841968 |
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| Order / More Info | Chk2 Inhibitor from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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