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| Product Name | Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-261) protein |
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| Description | Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.Alternative Names: Heme Oxygenase 1, HO-1, HMOX1, HO, HO1 |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HMOX1|HO1|MGC132176|wu:fc27c04|zgc:65984|ARABIDOPSIS THALIANA HEME OXYGENASE 1|ATHO1|F18A8.4|F18A8_4|GENOMES UNCOUPLED 2|GUN2|HEME OXYGENASE|HEME OXYGENASE 1|HEME OXYGENASE 6|HY1|HY6|PLASTID HEME OXYGENASE|REVERSAL OF THE DET PHENOTYPE 4|HMOX1D|HO-1|HSP32|bK286B10|D8Wsu38e|Hemox|Hmox|Hsp32|HEOXG|Heox|Ho-1|Ho1|hsp32|Hmox1 |
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| Gene, Accession, CAS # | Gene ID: 3162 |
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| Catalog # | ABIN1096830 |
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| Order / More Info | Heme Oxygenase (Decycling) 1 (HMOX1) (AA 1-261) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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