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Product Name | CD40 Ligand, Recombinant, Human |
Description | Purity ~95% (SDS-PAGE). CD40LG protein is expressed on all B lymphocytes during various stages of development, activated T cells and monocytes, follicular dendritic cells, thymic epithelial cells, and various carcinoma cell lines. It is expressed on most mature B cell malignancies and on some early B cell acute lymphocytic leukemias. Human CD40LG has been found to be the receptor for a protein involved in an X-linked immunodeficiency syndrome. Based on its homology with other members of the TNF ligand protein superfamily, CD40LG is also referred to also as TNFSF5. The soluble form of CD40LG is generated by the intracellular proteolytic processing of the full length CD40LG. Recombinant Human CD40LG is a 17kD protein that represents the soluble segment of full length CD40LG and encompasses the receptor binding TNF-like domain. Source: Recombinant protein corresponding to human CD40 Ligand expressed in E. coli. Molecular Weight: ~16kD Biological Activity: Determined by the dose-dependent proliferation of acute m |
Size | 50ug, 250ug |
Concentration | n/a |
Applications | n/a |
Other Names | CD40 Ligand, Recombinant, Human (Soluble CD40 Ligand, Tumor necrosis factor ligand superfamily member 5, TNFSF5, TNF-related activation protein, TRAP, CD154, gp39, T-BAM, CD40, T cell antigen Gp39, CD-40L) |
Gene, Accession, CAS # | SwissProt: P29965 |
Catalog # | 499862 |
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Order / More Info | CD40 Ligand, Recombinant, Human from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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