| 产品详情 |
| Edit |   |
|---|
| Product Name | CD40 Ligand, Recombinant, Human, Animal Free |
|---|
| Description | Purity ~98% (SDS-PAGE gel, HPLC). CD40 is a member of the TNF receptor family. it is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to ?immunodeficiency with hyper-IgM, a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261aa type II transmembrane protein, which contains a 22aa cytoplasmic domain, a 24aa transmembrane domain and a 215aa extracellular domain. The soluble form of CD40L is an 18kD protein comprising the entire TNF homologous region of CD40L. It is generated in vivo by an intracellular proteolytic processing of the full length CD40L. Source: Recombinant protein corre |
|---|
| Size | 10ug, 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | CD40 Ligand, Recombinant, Human, Animal Free (Soluble CD40 Ligand, TNFSF5, TRAP, CD154, gp39, T-BAM) |
|---|
| Gene, Accession, CAS # | n/a |
|---|
| Catalog # | 208608 |
|---|
| Price | |
|---|
| Order / More Info | CD40 Ligand, Recombinant, Human, Animal Free from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|