产品详情 |
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Product Name | 3,5-dimethyl PIT-1 |
Description | A selective nonphosphoinositide inhibitor with favorable solubility in vivo that specifically disrupts PIP3/Akt PH domain binding (IC50 = 27 µM); suppresses PI3K-PDK1-Akt-dependent phosphorylation, which reduces cell viability and induces apoptosis in PTEN-deficient U87MG glioblastoma cells (IC50 = 36 µM) |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | PIP3 PtdIns-(3,4,5)-P3 PH domain cancers inhibitors Akts PDK1 PTENs proteins binding inhibits inhibited inhibition DM-PIT-1 |
Gene, Accession, CAS # | CAS: 701947-53-7 |
Catalog # | 10727-1 |
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Order / More Info | 3,5-dimethyl PIT-1 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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