| 产品详情 |
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| Product Name | RI-1 |
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| Description | RI-1 is a potent and selective inhibitor of RAD51 (IC50 = 5-30 µM). It specifically reduces gene conversion in human cells and stimulates single strand annealing. It covalently binds to Cys319 on the surface of RAD51 and disrupts protein-protein interaction. It potentiates the effect of DNA-damaging agents on tumor cells and is a novel tool for studying DNA repair in cells. Potentiates the killing of glioblastoma cells by ionizing radiation and alkylating drugs. MW: 361.61. Purity ≥98% by TLC |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
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| Gene, Accession, CAS # | CAS: 415713-60-9 |
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| Catalog # | B1823-25 |
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| Order / More Info | RI-1 from BIOVISION, INC. |
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| Product Specific References | n/a |
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