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| Antigenic Specificity | FZR |
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| Clone | 1C7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 κ |
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| Format | Protein G purified |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FZR (1C7) Monoclonal Antibody. • Target Background: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA |
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| Immunogen | This FZR antibody is generated from a mouse immunized with a recombinant protein between1-496 amino acids from human FZR. |
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| Other Names | FZR; CDH1; FZR2; HCDH; HCDH1; CDC20C; Fizzy-related protein homolog; CDC20-like protein 1; Cdh1/Hct1 homolog; FZR1; FYR; KIAA1242 |
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| Gene, Accession # | Gene ID: 51343, SwissProt: Q9UM11 |
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| Catalog # | bsm-51345M |
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| Price | |
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| Order / More Info | FZR Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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