| 产品详情 |
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| Antigenic Specificity | SYPL2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | Immunofluorescence: 20 µg/mL, Immunohistochemistry: 2.5 µg/mL, Western Blot: 1 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SYPL2 Polyclonal Antibody. SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expre |
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| Immunogen | n/a |
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| Other Names | UNQ6348, MG29; mitsugumin 29; mitsugumin-29; synaptophysin-like protein 2 |
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| Gene, Accession # | Entrez: 17306, 284612, 362018; Uniprot: O89104, Q5VXT5 |
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| Catalog # | PA5-20776 |
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| Price | |
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| Order / More Info | SYPL2 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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