| 产品详情 |
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| Product Name | Recombinant Varicella-zoster virus Envelope glycoprotein E (gE) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 85.4kDa. Full Length of Mature Protein: 31-623aa. N-terminal 10xHis-SUMO-tagged. Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3). Envelope glycoprotein that binds to the potential host cell entry receptor IDE. In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | gE, UniProt: P09259 |
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| Catalog # | RPC20795 |
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| Order / More Info | Recombinant Varicella-zoster virus Envelope glycoprotein E (gE) from BIOMATIK |
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| Product Specific References | n/a |
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