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Product Name | Recombinant Human Rho guanine nucleotide exchange factor 7 (ARHGEF7), partial |
Description | Purity > 90% as determined by SDS-PAGE. MW: 54.8kDa. Partial: 1-250aa. N-terminal GST-tagged. Homo sapiens (Human). Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce mbrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions. May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.3 Publications |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Beta-PixCOOL-1; PAK-interacting exchange factor betap85 |
Gene, Accession, CAS # | ARHGEF7, UniProt: Q14155 |
Catalog # | RPC23962 |
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Order / More Info | Recombinant Human Rho guanine nucleotide exchange factor 7 (ARHGEF7), partial from BIOMATIK |
Product Specific References | n/a |
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