| 产品详情 |
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| Antigenic Specificity | DND1 |
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| Clone | 1F7 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay-Dependent, Immunocytochemistry: 10 µg/mL, Immunofluorescence: 10 µg/mL, Western Blot: 1-5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DND1 Monoclonal Antibody (1F7). RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity). |
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| Immunogen | n/a |
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| Other Names | Dead end homolog 1 (zebrafish), MGC34750, RBMS4 |
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| Gene, Accession # | Entrez: 373863; Uniprot: Q8IYX4 |
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| Catalog # | MA5-23282 |
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| Price | |
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| Order / More Info | DND1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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