| 产品详情 |
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| Antigenic Specificity | DcTRAIL-R2 |
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| Clone | mDcR2-1 |
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| Host Species | Armenian Hamster |
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| Reactive Species | mouse |
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| Isotype | IgG |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 25 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PE anti-mouse DcTRAIL-R2. Mouse Decoy Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor 2 (mDcTRAIL-R2) is highly homologous to mDcTRAIL R1. It is a GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain. It is expressed on many cell types, including some tumor cells. It was reported that overexpression of mDcTRAIL-R2 did not induce caspase activation that is characteristic of death receptor signaling. mDcTRAIL-R2 appears to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcTRAIL-R2 in apoptosis has not yet been completely clarified. |
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| Immunogen | mDcTRAIL-R2-Fc |
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| Other Names | TNFRH2, Tnfrsf22, SOBa, Tnfrsf1al2, mDcTrailr2, tumor necrosis factor receptor superfamily member 22 |
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| Gene, Accession # | Gene ID: 79202 |
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| Catalog # | 133703 |
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| Price | |
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| Order / More Info | DcTRAIL-R2 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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