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| Product Name | IGFBP3, Recombinant, Mouse, Western Blot Positive Control |
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| Description | Highly Purified (~95%) . The insulin like growth factors (IGFs) are the major growth- promoting factors in the plasma. IGFs are secreted by a variety of cells and exert a multitude of effects on cellular survival, growth and differentiation. The A and B domains of IGFs are identical to insulin. IGF initiates their biological action through binding to the type IGF receptor (IGF-1R), a heterotrimeric protein complex with a tyrosine kinase activity. The IGF-IIR lacks the kinase activity and is actually identical to the mannose- 6-phophate receptor. Unlike most other peptide hormones, IGFs are complexed with specific binding proteins in the plasma known IGF Binding proteins (IGFBPs). At least 6 related IGFBPs (IGFBP1-6) have been well characterized. Recently, IGFBP-7/Mac25/prostacyclin- stimulating factor (PSF)/tumor adhesion factor (TAF) was originally identified as a cDNA derived from leptomeninges. These proteins are present in plasma in high concentration as compared to the membrane I |
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| Size | 100ul |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | IGFBP3, Recombinant, Mouse, Western Blot Positive Control (Insulin-like Growth Factor-binding Protein 3, IBP-3, IGF-binding Protein 3, IGFBP-3, IBP3) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I7661-16H10 |
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| Order / More Info | IGFBP3, Recombinant, Mouse, Western Blot Positive Control from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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