| 产品详情 |
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| Product Name | KN-62 |
| Description | MW: 721.84. Purity ≥98%. Background: Cell-permeable. KN-62 is a selective inhibitor of Ca?/calmodulin-dependent kinase type II (CaMKII; IC??= 900 nM). It binds directly to the calmodulin binding site of the enzyme. It does not affect the activity of several other kinases when tested at 10 uM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7 (IC?? = 15 nM). |
| Size | 1 mg, 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | [4-?[(2S)-?2-?[(5-?isoquinolinylsulfonyl)methylamino]-?3-?oxo-?3-?(4-?phenyl-?1-?piperazinyl)propyl]phenyl ester,? 5-?isoquinolinesulfonic acid] |
| Gene, Accession, CAS # | CAS: 127191-97-3 |
| Catalog # | MBS843290 |
| Price | |
| Order / More Info | KN-62 from MYBIOSOURCE INC. |
| Product Specific References | n/a |
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