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| Product Name | JNJ-10198409 |
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| Description | MW: 325.34. Purity ≥98% by HPLC. JNJ-10198409 is a potent; cell-permeable; ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell antiproliferative activity. It is selective for PDGF-beta kinase with IC50 values of 4.2 nM for PDGF-beta and 45 nM for PDGF-alpha kinase. Displays less activity towards Lck; c-Src; and Fyn while exhibiting little to no inhibition toward VEGFR; HER-2; Cdk's-1; -2; -4 &-7; bFGF |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3-Fluoro-N- (6; 7-dimethoxy-2; 4-dihydroindeno[1; 2-c]pyrazol-3-yl) phenylamine; N- (3-fluorophenyl)-2; 4-dihydro-6; 7-dimethoxy-Indeno[1; 2-c]pyrazol-3-amine; RWJ 540973] |
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| Gene, Accession, CAS # | CAS: 627518-40-5 |
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| Catalog # | MBS846225 |
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| Price | |
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| Order / More Info | JNJ-10198409 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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