| 产品详情 |
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| Product Name | GW 4869 dihydrocloride |
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| Description | MW: 577.5. Purity ≥90%. Background: GW 4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC?? = 1 muM), but does not affect acid sphingomyelinase activity. It inhibits TNF-alpha-mediated sphingomyelin hydrolysis (100% inhibition at 20 muM) and TNF-alpha-induced cell death in MCF7 cells without interfering with activation of NF-kappaB or glutathione depletion in response to TNF. |
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| Size | 1 mg, 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [3,?3'-?(1,?4-?phenylene)bis[N-?[4-?(4,?5-?dihydro-?1H-?imidazol-?2-?yl)phenyl]-?2-?propenamide; dihydrochloride; GW69A; GW554869A] |
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| Gene, Accession, CAS # | CAS: 6823-69-4 |
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| Catalog # | MBS842766 |
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| Order / More Info | GW 4869 dihydrocloride from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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