产品详情 |
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Antigenic Specificity | PSMB10 (aa 231-242) |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat Anti-Human PSMB10 (aa 231-242) polyclonal antibody for WB. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008] |
Immunogen | Synthetic peptide |
Other Names | n/a |
Gene, Accession # | Gene ID: 5699, UniProt: P40306 |
Catalog # | CABT-BL5457 |
Price | |
Order / More Info | PSMB10 (aa 231-242) Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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