产品详情 |
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Product Name | 3,5-Diiodothyropropionic Acid |
Description | An inotropic thyroid hormone analogue of L-thyroxine; binds to TRα and TRβ (Kas = 2.4 and 4.06 x 107 M-1, respectively, for human recombinant receptors); increases mRNA expression of α-MHC in primary rat cardiomyocytes (EC50 = ~0.5 µM); prevents myocardial infarction-induced loss of contractility ex vivo in rabbit cardiomyocytes (3.75 mg/kg per day); increases expression of VEGF, bFGF, angiopoietin-1, and Tie-2 as well as angiogenesis in non-infarcted cardiac tissue in rats (3.75 mg/kg per day); decreases infarct size expansion, stimulates arteriolar growth, and inhibits ventricular remodeling post-myocardial infarction in rats (3.5 mg/kg per day) |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | DITPA |
Gene, Accession, CAS # | CAS: 1158-10-7 |
Catalog # | 23299-25 |
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Order / More Info | 3,5-Diiodothyropropionic Acid from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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