| 产品详情 |
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| Antigenic Specificity | DFF40 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | 0.2 mg/ml |
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| Applications | Western blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DFF40 Antibody. DFF is composed of two subunits: DFF40/CAD and DFF45/ICAD. Human DFF45 and its mouse homologue ICAD are the inhibitors of DFF40 and CAD, respectively. Cleavage of DFF45, which is mediated by caspase-3, leads to DFF40's activation as a nuclease. Activation of DFF40/CAD can lead to DNA fragmentation, a hallmark of apoptosis. DFF40 mRNA is expressed in limited number of human tissues: pancreas, spleen, prostate, and ovary. |
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| Immunogen | Synthetic peptide surrounding amino acid 208 of mouse DFF40 |
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| Other Names | DFFB, CAD, DFF-40 , CPAN , DFF2 |
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| Gene, Accession # | Gene ID: 13368, Accession: AAH53052 |
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| Catalog # | 3049-100 |
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| Price | |
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| Order / More Info | DFF40 Antibody from BIOVISION, INC. |
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| Product Specific References | n/a |
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