产品详情 |
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Product Name | Butyrolactone I |
Description | A Cdk1 inhibitor (IC50 = 20 µg/ml in PC-14 cells); induces dose-dependent G2/M arrest, inhibits DNA synthesis, and decreases Cdk1 protein expression in vitro; has antitumor effects in non-small lung, small cell lung, and prostate cancer cell lines (average IC50 = 50 µg/ml); inhibits in vitro Cdk1 phosphorylation of tau; inhibits in vivo phosphorylation of transcription factor E2F-1; increases biogenesis of the secondary metabolite lovastatin and conidiation in A. terreus, |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 65372-42-1 olomoucin 4'-O-demethylversicolactone D aspergillus Cdk-1 G-2 E2F1 anti-tumor demethyl versicolactone NSCLC PC14 |
Gene, Accession, CAS # | CAS: 87414-49-1 |
Catalog # | 21765-1 |
Price | |
Order / More Info | Butyrolactone I from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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