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| Antigenic Specificity | SF3a120/SAP114 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SF3a120/SAP114 Polyclonal Antibody. This gene encodes subunit 1 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 1 belongs to the SURP protein family; named for the SURP motifs that are thought to mediate RNA binding. Subunit 1 has tandemly repeated SURP motifs in its amino-terminal half while its carboxy-terminal half contains a proline-rich region and a ubiquitin-like domain. Binding studies with truncated subunit 1 derivatives demonstrated that the two SURP motifs are necessary for binding to subunit 3 while contacts with subunit 2 may occur through se |
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| Immunogen | n/a |
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| Other Names | Splicing factor 3a, PRP21, PRPF21, SAP114, SF3A120 |
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| Gene, Accession # | Entrez: 10291; Uniprot: Q15459 |
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| Catalog # | A301-604A |
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| Price | |
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| Order / More Info | SF3a120/SAP114 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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