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| Product Name | Flupirtine (maleate) |
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| Description | Purity >95%. Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, which are expressed predominantly in the nervous system but may also be found on smooth muscle and other sites. It doubles channel currents when applied at 10 µM. Through its effects on KCNQ channels, flupirtine serves as a centrally-acting analgesic with muscle tone-reducing activity. It is poorly metabolized by liver microsomal preparations and is, instead, targeted by peroxidases, including myeloperoxidase. Flupirtine also decreases neurotoxicity associated with prion disease, reducing cognitive decline in patients with Creutzfeldt-Jakob disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid, ethyl ester, 2Z-butenedioate |
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| Gene, Accession, CAS # | CAS: 75507-68-5 |
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| Catalog # | LS-H7824 |
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| Order / More Info | Flupirtine (maleate) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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