| 产品详情 |
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| Antigenic Specificity | GP130 |
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| Clone | 125623 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2A |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Flow Cytometry: 2.5 µg/1x10^6 cells, Immunocytochemistry: 8-25 µg/mL, Immunofluorescence: 8-25 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GP130 Monoclonal Antibody (125623). The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinc |
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| Immunogen | n/a |
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| Other Names | CD130, CDw130, GP130, GP130-RAPS, IL6R-beta, IL6ST |
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| Gene, Accession # | Entrez: 16195; Uniprot: Q00560 |
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| Catalog # | MA5-23922 |
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| Price | |
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| Order / More Info | GP130 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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