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| Product Name | Recombinant Human Growth/differentiation factor 15 (GDF15), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 16.4kDa. Partial: 197-308aa. N-terminal 6xHis-tagged. Homo sapiens (Human). Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Macrophage inhibitory cytokine 1 (MIC-1) (NSAID-activated gene 1 protein) (NAG-1) (NSAID-regulated gene 1 protein) (NRG-1) (Placental TGF-beta) (Placental bone morphogenetic protein) (Prostate differentiation factor) (GDF-15) |
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| Gene, Accession, CAS # | GDF15, UniProt: Q99988 |
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| Catalog # | RPC26149 |
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| Price | |
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| Order / More Info | Recombinant Human Growth/differentiation factor 15 (GDF15), partial from BIOMATIK |
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| Product Specific References | n/a |
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