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| Antigenic Specificity | CD262 |
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| Clone | DJR2-4 |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgG1 |
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| Format | n/a |
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| Size | 0.025 mg |
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| Concentration | IgG concentration 0.5mg/ml |
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| Applications | Flow cytometry (FC/FACS), Immunofluorescence (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | MOUSE ANTI HUMAN CD262. This item recognises human CD262, also known as Death receptor 5 (DR5) and TNF-related apoptosis-inducing ligand receptor 2 (TRAIL-R2). It is a 55kDa member of the TNF receptor superfamily binding tumor necrosis factor-related apoptosis inducing ligand (TNFSF10, TRAIL or APO-2L). Once activated, this receptor induces a cascade of caspases resulting in apoptosis. FADD, a death domain containing adaptor protein is required for apoptosis mediated by DR5. DR5 is widely expres |
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| Immunogen | Extracellular domain of DR5-human IgG1 Fc fusion protein |
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| Other Names | tumor necrosis factor receptor superfamily member 10B isoform 1; Tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; p53-regulated DNA damage-inducible cell death |
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| Gene, Accession # | CD262, Gene ID: 8795, NCBI: NP_003833.4, UniProt: O14763 |
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| Catalog # | MBS219128 |
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| Price | |
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| Order / More Info | CD262 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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