| 产品详情 |
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| Antigenic Specificity | p53AIP1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunohistochemistry: 1:200-1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | p53AIP1 Polyclonal Antibody. The novel protein p53AIP, p53-regulated apoptosis-inducing protein 1, has been identified from the direct cloning of p53 binding sequences from human genomic DNA. The expression of p53AIP1 in mitochondria is induced by wild-type p53, which leads to apoptotic cell death through dissipation of mitochondrial Dym. Severe DNA damage causes the phosphorylation of p53 at Ser-46, p53AIP1 expression, and apoptotic cell death. DNA damage-inducible apoptotic cell death was enhanced through transcriptional activation of p53AIP1. P53R2 is directly regulated by p53 for supplying nucleotides to repair damaged DNA, thus plays a pivotal role in cell survival by repairing damaged DNA in the nucleus and that dysfunction of this pa |
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| Immunogen | n/a |
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| Other Names | P53AIP1; p53-regulated apoptosis-inducing protein 1 |
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| Gene, Accession # | Entrez: 63970; Uniprot: Q9HCN2 |
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| Catalog # | PA5-61819 |
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| Price | |
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| Order / More Info | p53AIP1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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