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| Product Name | JNJ 16259685 |
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| Description | Sub-nanomolar potent, non-competitive mGlu1 antagonist (Ki = 0.34 nM). Inhibits glutamate-induced Ca2+ response at the human mGlu1 receptor with an IC50 value of 0.55 nM. Selective over mGlu5 (> 400-fold) and displays no activity at mGlu2, mGlu3, mGlu4, mGlu6, AMPA or NMDA receptors (IC50 > 10 μM). Centrally active following systemic administration. Purity 98%. MW (observed): 325.41 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone |
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| Gene, Accession, CAS # | CAS: 409345-29-5 |
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| Catalog # | 2333/50 |
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| Price | |
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| Order / More Info | JNJ 16259685 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 17502847, 18174329, 19657020, 21753005, 24205371, 24270186, 24467847, 26269634, 26655894, 27807163 |
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