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| Antigenic Specificity | HLA-DQB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HLA-DQB1 Polyclonal Antibody. HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorp |
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| Immunogen | n/a |
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| Other Names | HLA-DQB1, HLA-DQB, IDDM1, major histocompatibility complex, class II, DQ beta 1, CELIAC1 |
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| Gene, Accession # | Entrez: 3119; Uniprot: P01920 |
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| Catalog # | PA5-78003 |
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| Price | |
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| Order / More Info | HLA-DQB1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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