| 产品详情 |
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| Antigenic Specificity | Leptin Receptor |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blot: 1:2,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Leptin Receptor Polyclonal Antibody. The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance. Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway. Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains. Several isoforms of the OB-R which differ in length and signaling capabilities have been reported. RNA transcripts encoding the OB-R long form have been found in the |
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| Immunogen | n/a |
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| Other Names | OB-R, LEP-R, OB receptor, HuB219, CD295 antigen, LEPR , leptin receptor , CD295, OBR , OB receptor, LeprB |
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| Gene, Accession # | Entrez: 16847, 24536, 3953; Uniprot: P48356, P48357, Q62959 |
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| Catalog # | PA1-053 |
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| Price | |
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| Order / More Info | Leptin Receptor Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11404285, 11590224, 11967222, 12810558, 15059958, 16037380, 20308782, 23895348, 9421392 |
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