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| Product Name | BioSim™ anti-Avelumab (Bavencio®) (Human) ELISA Kit |
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| Description | Avelumab (Bavencio®) is a fully human anti-PD-L1 IgG1 lambda monoclonal antibody that has a molecular weight of approximately 147 kDa. Avelumab binds PD-L1 and blocks the interaction between PD-L1 and its receptors PD-1 and B7-1. By inhibiting PD-L1 interactions, avelumab is thought to enable the activation of T-cells and the adaptive immune system. By retaining anative Fc-region, avelumab is thought to engage the innate immune system and may induce antibody-dependent cell-mediated cytotoxicity. Importantly, avelumab has not shown antibody-dependent cell mediated cytotoxicity against immune cell subsets in humans. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivatin |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for Qualitative determination of antibody against Avelumab (Bavencio) in serum and plasma |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E4557-100 |
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| Order / More Info | BioSim™ anti-Avelumab (Bavencio®) (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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