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| Product Name | BioSim™ anti-Nivolumab (Opdivo®) (Human) ELISA Kit |
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| Description | Nivolumab (Opdivo®) is a human immunoglobulin G4 (IgG4) monoclonal antibody that binds to the programmed cell death 1 (PD-1) receptor and selectively blocks interaction with its programmed death ligands PD-L1 and PD-L2. Upregulation of PD-1 ligands occurs in some tumors and signalling through this pathway can contribute to inhibition of active T-cell immune surveillance of tumour tissue. The inhibitory effect of PD-1 and its ligands occurs through the promotion of apoptosis in antigen specific T cells while simultaneously blocking apoptosis in suppressor T cells. Blocking PD-1 activity has been shown to lead to decreased tumour growth in mouse tumour models. However, some patients develop unwanted immunogenicity, which leads to producti |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | This ELISA kit is used for Qualitative determination of antibody against Nivolumab (Opdivo) in serum and plasma |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | E4396-100 |
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| Order / More Info | BioSim™ anti-Nivolumab (Opdivo®) (Human) ELISA Kit from BIOVISION, INC. |
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| Product Specific References | n/a |
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