产品详情 |
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Antigenic Specificity | ATM (Phosphorylated S1981) |
Clone | E12 |
Host Species | Recombinant Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1, κ |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB, IHC, ICC, IF, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-ATM (Phosphorylated S1981) Recombinant Antibody (E12). Provided herein is a Mouse monoclonal antibody against ATM Serine/Threonine Kinase. The antibody can be used for immunoassay techniques, such as WB, IHC, ICC, IF, IHC-P. ATM belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damag |
Immunogen | Synthetic peptide made to a region surrounding the phosphorylated Serine 1981 of human ATM. |
Other Names | ATM Serine/Threonine Kinase; Ataxia Telangiectasia Mutated; A-T Mutated; EC 2.7.11.1; Ataxia Telangiectasia Mutated (Includes Complementation Groups A, C And D); TEL1, Telomere Maintenance 1, Homolog (S. Cerevisiae); TEL1, Telomere Maintenance 1, Homolog; Serine-Protein Kinase ATM; AT Mutated; |
Gene, Accession # | Gene ID: 472, UniProt: Q13315 |
Catalog # | PTM-CBMAB-0051YC |
Price | |
Order / More Info | ATM (Phosphorylated S1981) Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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