| 产品详情 |
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| Antigenic Specificity | DLL4 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA: 1:3000-1:15,000, Immunohistochemistry (Paraffin): 5-15 µg/mL, Western Blot: 1:300-1:1500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DLL4 Polyclonal Antibody. Delta-like ligand 4 (DLL4), also know as Delta-4, is a homologue of the Drosophila delta protein, and functions as a transmembrane bound ligand to the notch receptor Notch1. DLL4 is expressed in the vasculature and plays a critical role in vascular development. It is induced by vascular endothelial growth factor (VEGF), as a negative feedback regulator to regulate angiogenic sprouting and promote the formulation of a differentiated vascular network. DLL4 has been found to be strongly expressed in tumor vessels of clear-cell renal tumors and bladder cancer, and inhibition of DLL4 results in increased vascular proliferation but defective maturation. This in turn leads to a decrease in tumor growth, with no apparent t |
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| Immunogen | n/a |
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| Other Names | MGC126344, hdelta2 |
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| Gene, Accession # | Entrez: 54567; Uniprot: Q9NR61 |
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| Catalog # | PA1-86897 |
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| Price | |
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| Order / More Info | DLL4 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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