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| Antigenic Specificity | CD55 |
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| Clone | JS11 |
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| Host Species | Mouse |
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| Reactive Species | human, African green, baboon, cynomolgus |
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| Isotype | IgG1, κ |
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| Format | TotalSeq™-A oligomer conjugate |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | Proteogenomics. TotalSeq™ reagents are designed to profile protein expression at a single cell level following an optimized protocol similar to the CITE-seq workflow. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TotalSeq™-A0383 anti-human CD55. CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known as decay-accelerating factor (DAF). It is expressed on hematopoietic cells including erythrocytes and many non-hematopoietic cells. CD55 accelerates the dissociation of the components of the C3-convertases (namely C2a from C4b in the C4bC2a complex, a C3-convertase of the classical pathway, and factor Bb from the C3bBb complex, a C3-convertase of the alternative pathway) to protect cells from inappropriate damage caused by autologous complement. CD55 has been reported to reduce the efficiency of NK cell lysis and induce signal transduction in T cells. CD55 has also been shown to interact with CD97 and bind to Coxsackie and Echovirus. |
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| Immunogen | n/a |
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| Other Names | DAF (Decay Accelerating Factor) |
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| Gene, Accession # | Gene ID: 1604 |
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| Catalog # | 311317 |
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| Price | |
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| Order / More Info | CD55 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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