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| Antigenic Specificity | T-Cell Leukemia/lymphoma 1A (TCL1A) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TCL1 (T cell leukemia 1), MTCP1 and TCL1b belong to the TCL1 proto-oncogene family, and their products are involved in Akt activation during embryonic development, T cell leukemias, prolymphocytic leukemias and B cell lymphomas . The Akt association domain of TCL1 binds with the PH domain of Akt. The formation of an oligomeric TCL-Akt complex is required for TCL1 coactivator function and results in phosphorylation and activation of Akt . Furthermore, functional analysis indicates that the interaction between TCL1 and Akt promotes translocation of Akt to the nucleus . These findings are supported by the crystal structure of TCL1, which suggests that TCL1 may participate in molecular transport . Synonyms: TCL1A,TCL1 , |
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| Immunogen | Recombinant protein of human TCL1A |
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| Other Names | TCL1A|Tcl1a|TCL1|Tcl1 |
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| Gene, Accession # | Gene ID: 8115,21432,690575 |
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| Catalog # | ABIN1684034 |
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| Price | |
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| Order / More Info | T-Cell Leukemia/lymphoma 1A (TCL1A) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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