| 产品名称 |
IKK gamma, NT, Blocking Peptide (IKK3, NEMO, FIP3, IKKAP1, IkappaB Kinase gamma, IKKg) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IKK gamma, NT, Blocking Peptide (IKK3, NEMO, FIP3, IKKAP1, IkappaB Kinase gamma, IKKg) |
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| Description | Purified 60-70%. Peptide (CQYQAPDMDTLQIHVME) corresponding to amino acids 400 to 416 of human IKKg (1,2), which are identical to those of mouse homologue (2). Nuclear factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and in?ammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-kB activity. The IkB kinase (IKKa and IKKb) phosphorylates IkB and mediates NF-kB activation. A novel molecule in the IKK complex was recently identi?ed and termed IKKg/NEMO/FIP3/IKKAP1 (1-5). IKKg interacts with IKKb and is required for the activation of IKK complex and NF-kB by LPS, PMA, TNF, and IL-1 stimulation (1-4). FIP3 was also shown to bind to RIP and NIK and to mediate TNF-induced NF-kB activation(3). Applications: Suitable for use in ELISA and Western Blot. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I3000-65P |
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| Order / More Info | IKK gamma, NT, Blocking Peptide (IKK3, NEMO, FIP3, IKKAP1, IkappaB Kinase gamma, IKKg) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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