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Product Name | Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-151) protein (His tag) |
Description | Bone Morphogenetic Protein Receptor II (BMPR-II) is a Type II Serine/Threonine Kinase that mediates cellular responses to BMPs. BMPR-II is characterized by lacking of a GS domain, and presence of a C-terminal extension typical of type II receptors. BMPRII binds BMP2, BMP4 and BMP7 weakly in the absence of type I receptor, and the binding can be facilitated by the presence of the type I receptor, including BMPR-IA/Brk1, BMPR-IB, and ActR-I. BMPR-II plays a key role in cell growth. Defects in BMPR-II have been linked to primary pulmonary hypertension. Human and mouse BMPR-II are highly conserved and share 97 % amino acid sequence identity.Alternative Names: Bone Morphogenetic Protein Receptor Type-2, BMP Type-2 Receptor, BMPR-2, Bone Morphogenetic Protein Receptor Type II, BMP Type II Receptor, BMPR-II, BMPR2, PPH1 |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BMPR-II|BMPR3|BMR2|BRK-3|PPH1|T-ALK|2610024H22Rik|AL117858|AW546137|BB189135|BMP-2|BMPR-2|BMPRII|Gm20272|Bmpr-II|bmprii |
Gene, Accession, CAS # | Gene ID: 659 |
Catalog # | ABIN1096144 |
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Order / More Info | Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2) (AA 27-151) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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