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Product Name | Heat Shock Protein 70 (HSP70) BioAssay™ ELISA Kit |
Description | Heat Shock Protein 70 (Hsp70) BioAssay™ ELISA Kit is a colorimetric sandwich immunoassay for the quantitative determination of inducible Heat Shock Protein (Hsp70) in serum and EDTA plasma samples of human, mouse and rat origin. It does not detect other Hsp70 family members such as Hsc70 (Hsp73), rp78, DnaK (E. coli), or Hsp71 (M. tuberculosis). The Hsp70 family of heat shock proteins contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the |
Size | 1 kit |
Concentration | n/a |
Applications | ELISA |
Other Names | n/a |
Gene, Accession, CAS # | SwissProt: P0DMV8 (HSPA1A), P0DMV9 (HSPA1B) |
Catalog # | H1834-37 |
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Order / More Info | Heat Shock Protein 70 (HSP70) BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
Product Specific References | n/a |
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