| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Lipocalin 2 (LCN2) |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat, human |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Lipocalin-2, a member of the lipocalin family of proteins, was originally identified as a gelatinase-associated component of neutrophil secretory granules. Lipocalin-2 is involved in innate immunity, iron homeostasis, and apoptosis. Lipocalin-2 limits bacterial growth by binding to bacterial siderophores and sequestering iron. In mammalian cells, iron-loaded lipocalin-2 binds to its receptor, 24p3R, and is internalized, thereby releasing iron and increasing the intracellular iron concentration. Conversely, iron-free lipocalin-2 promotes apoptosis. Lipocalin-2 is also expressed in adipose tissue and promotes insulin resistance in cultured mouse adipocytes.Synonyms: LCN2, 24p3, MSFI, NGAL, Lipocalin-2 |
|---|
| Immunogen | Recombinant protein of human LCN2 |
|---|
| Other Names | LCN2|24p3|MSFI|NGAL|AW212229|Sip24 |
|---|
| Gene, Accession # | Gene ID: 3934,16819,170496 |
|---|
| Catalog # | ABIN1513147 |
|---|
| Price | |
|---|
| Order / More Info | Lipocalin 2 (LCN2) Antibody from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|