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| Product Name | HLCL-61 hydrochloride |
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| Description | MW: 380.92. Purity ≥98% by HPLC. HLCL-61 is a potent and selective PRMT5 (potent arginine methyltransferase 5) inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members. In vitro data shows HLCL-61 effectively inhibits symmetric arginine demethylation of histones H3 and H4 in AML samples. HLCL-61 treatment of cells showed decrease in cell vitality and effective in apoptosis promotion in MV-11 and THP-1 cells after 48 hours. |
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| Size | 5 mg, 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [1- (9-ethyl-9H-carbazol-3-yl)-N- (2-methoxybenzyl) methanamine hydrochloride] |
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| Gene, Accession, CAS # | CAS: 586395-74-6 |
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| Catalog # | MBS846351 |
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| Order / More Info | HLCL-61 hydrochloride from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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