| 产品详情 |
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| Product Name | NVP-TAE684 |
| Description | A potent and selective ALK (anaplastic lymphoma kinase) inhibitor that blocked the growth of ALCL (anaplastic large cell lymphoma)-derived and ALK-dependent cell lines with IC50 = 2-10 nM. NVP-TAE684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK (Nucleophosmin-anaplastic lymphoma kinase) and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest. MW: 614.2. Purity ≥98% by HPLC |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl-N2-(2-methoxy-4-(4-methylpiperazin-1-yl)-piperidin-1-yl)phenyl)pyrimidine-2,4-diamine |
| Gene, Accession, CAS # | CAS: 761439-42-3 |
| Catalog # | 1683-5 |
| Price | |
| Order / More Info | NVP-TAE684 from BIOVISION, INC. |
| Product Specific References | n/a |
| 产品资料 |
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