产品详情 |
Edit |   |
Product Name | NVP-TAE684 |
Description | A potent and selective ALK (anaplastic lymphoma kinase) inhibitor that blocked the growth of ALCL (anaplastic large cell lymphoma)-derived and ALK-dependent cell lines with IC50 = 2-10 nM. NVP-TAE684 treatment resulted in a rapid and sustained inhibition of phosphorylation of NPM-ALK (Nucleophosmin-anaplastic lymphoma kinase) and its downstream effectors and subsequent induction of apoptosis and cell cycle arrest. MW: 614.2. Purity ≥98% by HPLC |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-Chloro-N4-(2-(isopropylsulfonyl)phenyl-N2-(2-methoxy-4-(4-methylpiperazin-1-yl)-piperidin-1-yl)phenyl)pyrimidine-2,4-diamine |
Gene, Accession, CAS # | CAS: 761439-42-3 |
Catalog # | 1683-5 |
Price | |
Order / More Info | NVP-TAE684 from BIOVISION, INC. |
Product Specific References | n/a |
产品资料 |
|
|