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Product Name | Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-407) (Active) protein (His tag) |
Description | IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders. |
Size | 50 µg |
Concentration | n/a |
Applications | SDS-PAGE (SDS) |
Other Names | INDO|ido|indo|IDO|cd107b|IDO1|IDO-1|Ido|Indo |
Gene, Accession, CAS # | Gene ID: 15930 |
Catalog # | ABIN1344081 |
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Order / More Info | Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-407) (Active) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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