| 产品详情 |
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| Antigenic Specificity | ITM2B |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITM2B Polyclonal Antibody. Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. |
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| Immunogen | n/a |
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| Other Names | ABRI, BRI, BRI2, BRICD2B, E25B, E3-16, FBD, ABri/ADan amyloid peptide, BRICHOS domain containing 2B, transmembrane protein BRI |
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| Gene, Accession # | Entrez: 16432, 9445; Uniprot: O89051, Q9Y287 |
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| Catalog # | PA5-31441 |
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| Price | |
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| Order / More Info | ITM2B Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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