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| Antigenic Specificity | TNK1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 1:500 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TNK1 Polyclonal Antibody. Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity. |
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| Immunogen | n/a |
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| Other Names | Non-receptor tyrosine-protein kinase TNK1, Kinase of embryonic stem cells |
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| Gene, Accession # | Entrez: 83813; Uniprot: Q99ML2 |
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| Catalog # | PA1-4332 |
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| Price | |
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| Order / More Info | TNK1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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