| 产品详情 |
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| Product Name | Calyculin A (Serine/Threonine Phosphatase Inhibitor) |
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| Description | Purity ~98%. Calyculin A inhibits the activity of protein phosphatases PP1 and PP2A (1,2). Unlike Okadaic acid, which reduces PP2A activity but has little effect on PP1 activity, calyculin A inhibits both phosphatases (1). Neither calyculin A nor Okadaic acid inhibit acid or alkaline phosphatases or phosphotyrosine protein phosphatases (2). Calyculin A (Serine/Threonine Phosphatase Inhibitor) is a much more potent phosphatase inhibitor than Okadaic acid (2). As shown in the first Western blot, treating cells with 100nM Calyculin A for 30 minutes can dramatically induce threonine phosphorylation as detected by this antibody. IC50 values for inhibitory activity against PP1 are around 2nM. IC50 values for inhibitory activity against PP2A are around 0.5-1nM. Applications: Suitable for use as an inhibitor of protein phosphatases PP1 and PP2A. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C1036-72 |
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| Order / More Info | Calyculin A (Serine/Threonine Phosphatase Inhibitor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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